Pharmacokinetic and Pharmacodynamic Characteristics of Dasiglucagon, a Novel Soluble and Stable Glucagon Analog.

Ulrike HoevelmannBritta Væver BystedUlrik MouritzenFrancesca MacchiDaniela LamersBirgit KronshageDaniél Vega MøllerTim Heise

Published in: Diabetes care (2017)

Dasiglucagon was well tolerated and showed an early PD response similar to that of GlucaGen at corresponding doses, suggesting comparable clinical effects of the two glucagon formulations. Dasiglucagon has the potential to become an effective and reliable rescue treatment for severe hypoglycemia in a ready-to-use pen.

Keyphrases

type diabetes
early onset
adipose tissue
risk assessment
metabolic syndrome
glycemic control
skeletal muscle
human health
drug induced