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PEGylated Perylenemonoimide-Dithienylethene for Super-Resolution Imaging of Liposomes.

Jun-Xia LiuBo XinChong LiNuo-Hua XieWen-Liang GongZhen-Li HuangMing-Qiang Zhu
Published in: ACS applied materials & interfaces (2017)
We have designed and synthesized an amphiphilic photoswitchable fluorophore, PEGylated perylenemonoimide-dithienylethene (PEG-PMI-DTE), which exhibits evident bistable photochromism, fluorescence switching, and fatigue resistance. The fine nanostructures of liposomes can be observed directly under super-resolution fluorescent microscopy by aid of the amphiphilic photoswitchable fluorophore as a staining agent, with an optical resolution of 30 nm.
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