The HMGB1 is increased in CSF of patients with an Anti-NMDAR encephalitis.

P AiX ZhangZ XieG LiuX LiuS PanHonghao Wang

Published in: Acta neurologica Scandinavica (2017)

Our results showed significant increases in CSF HMGB1, IL-6, and IL-17A (P < .05) in anti-NMDAR encephalitis patients. But between 3 months' mRS scores in anti-NMDAR encephalitis patients and CSF data, there was no correlation. Our study suggests that HMGB1 CSF levels are increased in patients with anti-NMDAR encephalitis and reflect the underlying neuroinflammatory process.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
machine learning
deep learning