Prospective cohort of AIDS patients screened for cryptococcal antigenaemia, pre-emptively treated and followed in Brazil.

Moara Alves Santa Bárbara BorgesJoão Alves de Araújo FilhoBruno de Jesus Silva Oliveira Isabela Silvério MoreiraVanessa Valadares de PaulaAngélica Lima de BastosRenata de Bastos Ascenço SoaresMarília Dalva Turchi

Published in: PloS one (2019)

CrAg screening for severely immunosuppressed PLHAs in Brazil yielded a prevalence of 7.9%. No difference was found in the prevalence of CrAg stratified by CD4 values (CD4 <100 versus CD4 101-199 cells/μl). No clinical nor laboratory factors predicted CrAg positivity, corroborating the need for the implementation of universal CrAg screening for PLHAs with CD4 <200 cells/μl in similar settings.

Keyphrases

induced apoptosis
end stage renal disease
cell cycle arrest
risk factors
newly diagnosed
healthcare
primary care
chronic kidney disease
peritoneal dialysis
oxidative stress
cell proliferation
patient reported outcomes