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Clinicopathological and molecular analyses of linearly expanded epithelial cells with β-catenin alterations, "β-catenin signature", in the normal fallopian tube.

Kei KoyamaDaichi MaedaMasahiko KitoDaisuke TamuraYukitsugu Kudo-AsabeHiroto KatohShumpei IshikawaHiroshi NanjoYukihiro TeradaAkiteru Goto
Published in: Histopathology (2020)
This is the first report of the CTNNB1 mutation in clusters of morphologically bland tubal epithelial cells. The results of this study indicate that β-catenin signatures are common, and they may be a part of diverse molecular alterations occurring in normal tubal epithelium.
Keyphrases
  • epithelial mesenchymal transition
  • cell proliferation
  • single molecule
  • gene expression
  • signaling pathway