Antithrombin and fibrinogen levels as predictors for plasma L-asparaginase activity in children with acute lymphoblastic leukemia.
Clémence MerlenArnaud BonnefoyCynthia AfeichYves ThéorêtCaroline LaverdièreJean-Marie LeclercGeorges-Etienne RivardPublished in: Pediatric blood & cancer (2019)
AT combined with fibrinogen levels could be used as a proxy to identify patients with therapeutic level of L-asparaginase activity in the absence of real-time asparaginase measurement during prolonged exposure to L-asparaginase.