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5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts.

Vilma DembitzHrvoje LalicIvan KodvanjBarbara TomicJosip BatinicKlara DubravcicDrago BatinicAntonio BedalovDora Visnjic
Published in: BMC cancer (2020)
AICAr induces differentiation in a subset of primary non-APL AML blasts, and these effects correlate with sensitivity to a well-known, potent DHODH inhibitor.
Keyphrases
  • acute myeloid leukemia
  • allogeneic hematopoietic stem cell transplantation