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Immunology: Meta-learning for T cell-receptor binding specificity and beyond.

Duolin WangFei HeYang YuDong Xu
Published in: Nature machine intelligence (2023)
Predicting whether T-cell receptors bind to specific peptides is a challenging problem as the majority of binding examples in the training data involves only a few peptides. A new approach employs meta-learning to improve predictions for binding to peptides for which no or little binding data exists.
Keyphrases
  • binding protein
  • electronic health record
  • dna binding
  • amino acid
  • data analysis
  • machine learning
  • transcription factor
  • deep learning