Cardiac involvement in classical or hypermobile Ehlers-Danlos syndrome is uncommon.
Sharon L PaigeKirstie M LechichElif Seda Selamet TierneyR Thomas CollinsPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2020)
Our results demonstrate that aortic dilation and valvular anomalies are uncommon in cEDS or hEDS patients. Given the lack of evidence, we do not recommend echocardiographic evaluation and surveillance in patients with cEDS and hEDS in the absence of clinical findings or positive family history.