Epidemiology and Outcomes of Neonatal Meningitis: Results of the Turkish Neo-meningitis Nationwide Study.
Mehmet Yekta OncelMehmet N CizmeciEda Karadag-OncelAysegul Elvan-TuzFuat Emre CanpolatMustafa Ali AkinSinan UsluMerih CetinkayaOmer ErdeveEsin Kocnull nullPublished in: The Pediatric infectious disease journal (2024)
In this nationwide study, neonatal meningitis was found to be associated with high mortality. Coagulase-negative Staphylococci was the most common causative microorganism followed by gram-negative bacteria. Severe clinical presentation with invasive mechanical ventilation and inotrope requirement, as well as concomitant sepsis, low birth weight status and lack of exposure to antenatal steroids, were found to be independent risk factors for mortality.
Keyphrases
- mechanical ventilation
- low birth weight
- preterm birth
- intensive care unit
- cerebrospinal fluid
- preterm infants
- cardiovascular events
- acute respiratory distress syndrome
- risk factors
- human milk
- pregnant women
- acute kidney injury
- respiratory failure
- early onset
- metabolic syndrome
- coronary artery disease
- cardiovascular disease
- insulin resistance
- extracorporeal membrane oxygenation
- adipose tissue
- type diabetes
- antimicrobial resistance