Login / Signup

[Scientific legacy of Professor A.A. Kasparov. Inductor of endogenous interferon Poludan in the treatment of ocular herpes and other corneal diseases].

El A KasparovaEvg A Kasparova
Published in: Vestnik oftalmologii (2024)
This article presents a retrospective analysis of the research findings by professor A.A. Kasparov, who developed and implemented a novel approach to treating ocular herpes. The treatment system is fundamentally different from the conventional chemotherapeutic approach and revolves around non-specific immunotherapy using an endogenous interferon inducer - a biosynthetic complex of polyriboadenylic and polyribouridylic acids, known as Poludan. This approach also incorporates personalized cell therapy based on Poludan, along with herpes vaccine aimed at preventing recurrence. The regenerative and antiviral properties of this approach have proven successful in treating other corneal conditions such as adenovirus infections, early postoperative bullous keratopathy, as well as in stimulation of epithelialization after refractive surgeries (photorefractive keratectomy, phototherapeutic keratectomy).
Keyphrases
  • cell therapy
  • stem cells
  • mesenchymal stem cells
  • dendritic cells
  • patients undergoing
  • optical coherence tomography
  • immune response
  • combination therapy
  • wound healing
  • bone marrow
  • optic nerve
  • free survival