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Distal radius and tibia bone microarchitecture impairment in female patients with diffuse systemic sclerosis.

M M Sampaio-BarrosJ C AlvarengaL TakayamaA P L AssadP D Sampaio-BarrosRosa Maria Rodrigues Pereira
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2019)
Bone microarchitecture in patients with dSSc, analyzed through HR-pQCT, showed impairment of trabecular and cortical bone at distal radius and tibia. Variables associated with hand involvement (acroosteolysis, quality of life-grip strength, and ROM) and disease duration may be considered prognostic factors of this bone impairment.
Keyphrases
  • bone mineral density
  • systemic sclerosis
  • prognostic factors
  • soft tissue
  • postmenopausal women
  • bone loss
  • interstitial lung disease
  • bone regeneration
  • rheumatoid arthritis
  • low grade
  • idiopathic pulmonary fibrosis