Distal radius and tibia bone microarchitecture impairment in female patients with diffuse systemic sclerosis.

M M Sampaio-BarrosJ C AlvarengaL TakayamaA P L AssadP D Sampaio-BarrosRosa Maria Rodrigues Pereira

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2019)

Bone microarchitecture in patients with dSSc, analyzed through HR-pQCT, showed impairment of trabecular and cortical bone at distal radius and tibia. Variables associated with hand involvement (acroosteolysis, quality of life-grip strength, and ROM) and disease duration may be considered prognostic factors of this bone impairment.

Keyphrases

bone mineral density
systemic sclerosis
prognostic factors
soft tissue
postmenopausal women
bone loss
interstitial lung disease
bone regeneration
rheumatoid arthritis
low grade
idiopathic pulmonary fibrosis