Plasma advanced glycation end products and the subsequent risk of microvascular complications in type 1 diabetes in the DCCT/EDIC.

Vincent M MonnierDavid R SellXiaoyu GaoSaul M GenuthJohn M Lachin Ionut Bebunull null

Published in: BMJ open diabetes research & care (2022)

pAGEs at TP1 are not superior to HbA1c for risk prediction, but glucose-derived pAGEs at three TPs and MetSOX remain robustly associated with progression of microvascular complications in type 1 diabetes even after adjustment for HbA1c and other factors.

Keyphrases

type diabetes
glycemic control
risk factors
cardiovascular disease
insulin resistance
blood glucose
metabolic syndrome
adipose tissue