Association between genetic polymorphisms and osteoarthritis development. Overview of systematic reviews.
Amanda Almeida BrisolaMileny Esbravatti Stephano ColovatiMirlene Cecilia Soares Pinho CernachRachel RieraRafael Leite PachecoGiuliana Raduan CrizolAna Luiza Cabrera MartimbiancoPublished in: International journal of rheumatic diseases (2022)
Based on low-quality to critically-low-quality systematic reviews, some gene polymorphisms seem to be associated with risk or protection for OA. Further high-quality studies are needed to validate these hypotheses, contribute to disease understanding, and possibly help the decision-making related to early diagnosis and treatment options for OA. PROSPERO register CRD42021234231.