Proton versus Photon Radiotherapy for Pediatric Central Nervous System Malignancies: A Systematic Review and Meta-Analysis of Dosimetric Comparison Studies.

Roberta CarbonaraAlessia Di RitoAngela MontiGiuseppe RubiniAngela Sardaro

Published in: Journal of oncology (2019)

Our analysis supports the evidence of dosimetric advantages of PBT over photon RT, especially in the dose sparing of normal growing tissues. Confirmations from wider well-designed studies are required.

Keyphrases

radiation therapy
monte carlo
case control
living cells
early stage
gene expression
locally advanced
radiation induced
squamous cell carcinoma
cerebrospinal fluid
single molecule
clinical evaluation