Peripherin diverts ciliary ectosome release to photoreceptor disc morphogenesis.
Robert S MoldayAndrew F X GoldbergPublished in: The Journal of cell biology (2017)
Formation of membrane discs in photoreceptor cells requires evagination of its ciliary plasma membrane by an unknown molecular mechanism. Salinas et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608081) show that peripherin (also known as peripherin-2 or peripherin-2/rds) diverts membrane traffic to photoreceptor disc formation by inhibiting ectosome release from the cilium.