Activation of Aromatic C-F Bonds by a N-Heterocyclic Olefin (NHO).

Debdeep MandalShubhadeep ChandraNicolás I NeumanAlok MahataArighna SarkarAbhinanda KunduSrinivas AngaHemant RawatCarola SchulzkeKaustubh R MoteBiprajit SarkarVadapalli ChandrasekharAnukul Jana

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)

A N-heterocyclic olefin (NHO), a terminal alkene selectively activates aromatic C-F bonds without the need of any additional catalyst. As a result, a straightforward methodology was developed for the formation of different fluoroaryl-substituted alkenes in which the central carbon-carbon double bond is in a twisted geometry.

Keyphrases

amino acid
transition metal
molecular docking
ionic liquid
room temperature
carbon dioxide
metal organic framework
gold nanoparticles
molecular dynamics simulations