Effect of Postoperative Analgesic Exposure to the Cannabinoid Receptor Agonist WIN55 on Osteogenic Differentiation and Spinal Fusion in Rats.
Chawon YunMeraaj S HaleemSoyoen JeongMark A OyerAdam J DriscollKevin Y ChangJonghwa YunJonathan PaulRyan J LubbeStuart R StockWellington K HsuErin L HsuPublished in: The Journal of bone and joint surgery. American volume (2021)
The identification of alternative treatments for postoperative pain following orthopaedic surgical procedures is crucial in combating the ongoing opioid abuse crisis. The endocannabinoid system may represent a viable alternative target for addressing orthopaedic postoperative pain.