Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae).

Thais A da Costa-SilvaGeanne A Alves ConservaAndrés J GalisteoAndre G TemponeJoão Henrique Ghilardi Lago

Published in: The journal of venomous animals and toxins including tropical diseases (2019)

This study showed the antileishmanial activity of compounds 1 and 2 isolated from N. oppositifolia. Furthermore, compound 2 demonstrated an antileishmanial activity towards amastigotes associated to an immunomodulatory effect.

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