Polygenic Risk Score for Coronary Artery Disease Improves the Prediction of Early-Onset Myocardial Infarction and Mortality in Men.
Hasanga D ManikpurageAida EslamiNicolas PerrotZhonglin LiChristian CouturePatrick MathieuYohan BosseBenoit J ArsenaultSébastien ThériaultPublished in: Circulation. Genomic and precision medicine (2021)
Our PRSCAD predicts MI incidence and all-cause mortality, especially in men aged between 40 and 51 years. PRS could optimize the identification and management of individuals at risk for CAD.
Keyphrases
- early onset
- coronary artery disease
- cardiovascular events
- late onset
- risk factors
- middle aged
- percutaneous coronary intervention
- coronary artery bypass grafting
- heart failure
- left ventricular
- type diabetes
- cardiovascular disease
- aortic stenosis
- bioinformatics analysis
- acute coronary syndrome
- transcatheter aortic valve replacement