Immune Checkpoint Blockade in Combination with Stereotactic Body Radiotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma.
Changqing XieAustin G DuffyGagandeep BrarSuzanne FioravantiDonna Mabry-HronesMelissa WalkerCecilia Monge BonillaBradford J WoodDeborah E CitrinElizabeth M Gil RamirezFreddy E EscorciaBernadette ReddJonathan M HernandezJeremy L DavisBillel GasmiDavid E KleinerSeth M SteinbergJennifer C JonesTim F GretenPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
The combination of ICI and SBRT has an acceptable safety profile and demonstrates a modest treatment benefit in patients with metastatic PDAC.