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Association between TLR2/TLR4 gene polymorphisms and COPD phenotype in a Greek cohort.

A ApostolouT KerenidiA MichopoulosK I GourgoulianisMichel NoutsiasA E GermenisM Speletas
Published in: Herz (2016)
Our findings support the notion that the presence of innate immune SNPs, such as functional polymorphisms of TLRs along with MBL deficiency, might exert a protective effect on the COPD phenotype, similar with other immune-mediated disorders.
Keyphrases
  • innate immune
  • chronic obstructive pulmonary disease
  • toll like receptor
  • inflammatory response
  • lung function
  • immune response
  • cystic fibrosis
  • replacement therapy
  • genome wide association