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Glutaminostatin: Another facet of glucagon as a regulator of plasma amino acid concentrations.

Yoshitaka Hayashi
Published in: Journal of diabetes investigation (2019)
Glucagon plays an essential role in robust feedback regulation between the liver and α-cells, and exerts suppressive or static effects on the plasma concentration of amino acids, especially glutamine. Thereby, "glutaminostatin" might be an alternative name in recognition of another facet of glucagon as a suppressor of plasma glutamine levels.
Keyphrases
  • amino acid
  • induced apoptosis
  • cell cycle arrest
  • oxidative stress
  • cell death
  • cell proliferation