The effects of the interaction of genetic predisposition with lifestyle factors on bladder cancer risk.
Evan Yi-Wen YuYu-Xiang LiuYa-Ting ChenQiu-Yi TangSiamak MehrkanoonShi-Zhi WangWen-Chao LiMaurice P ZeegersAnke WesseliusPublished in: BJU international (2022)
This large-scale cohort study shows that a genetic predisposition combined with unhealthy behaviours have a joint negative effect on the risk of developing BC. Behavioural lifestyle changes should be encouraged for people through comprehensive, multifactorial approaches, although high-risk individuals may be selected based on genetic risk.