A Methodology for the Assessment and Prioritization of Genetic Biocontainment Technologies for Engineered Microbes.
Stephen PayneScott WickPeter A CarrNicholas J GuidoPublished in: Applied biosafety : journal of the American Biological Safety Association (2024)
Developing an assessment framework with defined metrics produced a straightforward system for evaluating genetic biocontainment strategies intended for various real-world applications. Use of the methodology also provided insights into existing gaps in genetic biocontainment strategies, and by altering the metrics, can be applied to other biotechnologies.