Effect of an oxygen-generating scaffold on the viability and insulin secretion function of porcine neonatal pancreatic cell clusters.

Eun Mi LeeJi-In JungZahid AlamHee-Gyeong YiHeejin KimJin Woo ChoiSunghoon HurhYoung June KimJong Cheol JeongJaeseok YangKook-Hwan OhHee Chan KimByeong Chun LeeInho ChoiDong-Woo ChoCurie Ahn

Published in: Xenotransplantation (2018)

NPCCs in PDMS + CaO2 scaffolds show higher viability and insulin secretion than do NPCCs in PDMS scaffolds and control cells. Therefore, this oxygen-generating scaffold has potential for application in future islet transplantation studies.

Keyphrases

tissue engineering
induced apoptosis
cell therapy
cell cycle arrest
single cell
current status
stem cells
cell death
endoplasmic reticulum stress
case control
climate change