Sequential stimulation with different concentrations of BMP4 promotes the differentiation of human embryonic stem cells into dental epithelium with potential for tooth formation.

Qian LiSiqi ZhangYi SuiXiaoming FuYan LiShicheng Wei

Published in: Stem cell research & therapy (2019)

These results show that hES cells differentiated into DE after sequential stimulation with different concentrations of BMP4, and the DE thus generated showed odontogenic potential.

Keyphrases

embryonic stem cells
mesenchymal stem cells
induced apoptosis
endothelial cells
human health
cell cycle arrest
bone regeneration
induced pluripotent stem cells
signaling pathway
oral health