Tumor Volume Predicts for Pathologic Complete Response in Rectal Cancer Patients Treated With Neoadjuvant Chemoradiation.
Fan YangJordan HillAswin AbrahamSunita GhoshTanner SteedClay KurtzKurian JosephJihyun YunBrad WarkentinJoAnn ThaiTirath NijjarDiane SeverinKeith TankelAlysa FairchildNawaid UsmaniPublished in: American journal of clinical oncology (2022)
A tumor volume threshold of 37.3 cm 3 was identified as predictive for pCR in locally advanced rectal cancer patients receiving neoadjuvant chemoradiation. Tumors above this volume threshold corresponded to a greater than 78% probability of not achieving pCR. This information will be helpful at diagnosis for clinicians who are considering potential candidates for NOM.