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Impact of gallbladder hypoplasia on hilar hepatic ducts in biliary atresia.

Nanae MiyazakiShohei TakamiMami UemuraHironobu OikiMasataka TakahashiHiroshi KawashimaYutaka KanamoriTakako YoshiokaMureo KasaharaAtsuko NakazawaMayumi HigashiAyaka YanagidaRyuji HiramatsuMasami Kanai-AzumaJun FujishiroYoshiakira Kanai
Published in: Communications medicine (2024)
Together with the close correlation between gallbladder wall hypoplasia and liver damage in both mouse and human cases, these findings provide an insight into the critical role of SOX17-positive gallbladder walls in establishing functional bile duct networks in the hepatic hilus of neonates.
Keyphrases
  • endothelial cells
  • stem cells
  • oxidative stress
  • induced pluripotent stem cells
  • low birth weight
  • preterm infants