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Damaged bone microarchitecture by Trabecular Bone Score (TBS) and low appendicular muscle mass: main risk factors for vertebral and non-vertebral fractures in women with long-standing rheumatoid arthritis.

Felipe F SilvaGisela R MachadoAna C M RibeiroKarina R BonfiglioliAndrea Y ShimabucoCamille P FigueiredoLiliam M T GuerraValéria F CaparboRosa M R PereiraDiogo Souza Domiciano
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2024)
In women with long-term RA, markers of fractures differed between distinct skeletal sites (vertebral and non-vertebral). The magnitude of association of bone/muscle parameters with fracture (TBS for VF and appendicular muscle mass for NVF) was greater than that of the association between RA activity and fracture. TBS seems to have greater discriminative power than BMD to identify subjects with VF in long-standing RA.
Keyphrases
  • bone mineral density
  • rheumatoid arthritis
  • postmenopausal women
  • body composition
  • disease activity
  • ankylosing spondylitis
  • interstitial lung disease
  • systemic lupus erythematosus
  • skeletal muscle
  • hip fracture