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Covalent Organic Framework as a Heterogeneous Ligand for the Regioselective Oxidative Heck Reaction.

Jiyao HanXiaowei SunXiao WangQiong WangShenghuai HouXin SongYingqin WeiRongyu WangWenhua Ji
Published in: Organic letters (2020)
A simple imine-based covalent organic framework (COF) as heterogeneous ligand for PdII-promoted Heck reaction is reported. Good regioselectivity for a wide range of electronically unbiased olefins is obtained (linear/branched >100:1 in most cases). Related tests and density functional theory calculations are used to explore the reason underlying the high selectivity. This research opens a route for COF as an intriguing platform to control regioselectivity catalysis.
Keyphrases
  • density functional theory
  • molecular dynamics
  • water soluble
  • high throughput
  • electron transfer
  • molecular dynamics simulations
  • visible light