Evolutionary engineering improves tolerance for medium-chain alcohols in Saccharomyces cerevisiae.
Stephanie A Davis LópezDouglas Andrew GriffithBrian ChoiJamie H D CateDanielle Tullman-ErcekPublished in: Biotechnology for biofuels (2018)
We successfully generated S. cerevisiae strains that have improved tolerance toward medium-chain alcohols and have demonstrated that the causative mutations overcome inhibition of translation initiation by these alcohols.