Diurnal 11-ketotestosterone and 17-hydroxyprogesterone saliva profiles in paediatric classical congenital adrenal hyperplasia.

Ilja DubinskiSusanne Bechtold-Dalla PozzaMartin BidlingmaierJames HawleyBrian KeevilSonja KunzHannah Franziska NowotnyNicole ReischKatharina SchiergensLea TschaidseHeinrich Schmidt

Published in: Journal of pediatric endocrinology & metabolism : JPEM (2024)

11-Ketotestosterone shows circadian rhythmicity in our cohort and correlates with 17-hydroxyprogesterone. These findings serve as an important basis for prospective research into 11-oxygenated androgens as therapeutic markers in paediatrics. However, 11-ketotestosterone appears to be very dependent on BMI.

Keyphrases

preterm birth
body mass index
intensive care unit
emergency department
physical activity
weight loss