Vascular Function, Systemic Inflammation, and Coagulation Activation 18 Months after COVID-19 Infection: An Observational Cohort Study.

Loes H Willems Lotte M C JacobsLaszlo A GrohHugo Ten Cate Henri M H SpronkBoden Wilson-StoreyGerjon HanninkSander M J van KuijkChahinda Ghossein-DohaMagdi NagyDick H J ThijssenAndré S van PetersenMichiel C Warlé

Published in: Journal of clinical medicine (2023)

This study shows that 18 months after COVID-19 infection, the incidence of macrovascular dysfunction as defined by a constrictive response during carotid artery reactivity testing is not increased. Nonetheless, plasma biomarkers indicate sustained endothelial cell activation (vWF), systemic inflammation (IL-6), and extrinsic/common pathway coagulation activation (FVII:AT, TAT) 18 months after COVID-19 infection.

Keyphrases

oxidative stress
risk factors
high glucose