Efficacy and Safety of Naloxegol in Patients with Chronic Non-Cancer Pain Who Experience Opioid-Induced Constipation: A Pooled Analysis of Two Global, Randomized Controlled Studies.

William D CheyDarren M BrennerBrooks D CashMartin HaleJeremy AdlerMansi S JamindarCarol B RockettJune S AlmenoffEnoch BorteyJeffrey Gudin

Published in: Journal of pain research (2023)

In patients with chronic non-cancer pain, naloxegol 25mg and 12.5mg demonstrated significantly higher response rates and rapid and sustained improvements in OIC symptoms compared with PBO.

Keyphrases

chronic pain
pain management
papillary thyroid
squamous cell
neuropathic pain
double blind
phase iii
lymph node metastasis
squamous cell carcinoma
diabetic rats
clinical trial
high glucose
childhood cancer
phase ii