Noncanonical Thyroid Hormone Receptor α Action Mediates Arterial Vasodilation.
Daniela GeistG Sebastian HönesJanina GassenHelena KerpPetra KleinbongardGerd HeuschDagmar FührerLars Christian MoellerPublished in: Endocrinology (2021)
These results demonstrate that T3 acting through noncanonical TRα action affects cardiovascular physiology by inducing endothelium-dependent vasodilation within minutes via PI3K and eNOS activation.