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Noncanonical Thyroid Hormone Receptor α Action Mediates Arterial Vasodilation.

Daniela GeistG Sebastian HönesJanina GassenHelena KerpPetra KleinbongardGerd HeuschDagmar FührerLars Christian Moeller
Published in: Endocrinology (2021)
These results demonstrate that T3 acting through noncanonical TRα action affects cardiovascular physiology by inducing endothelium-dependent vasodilation within minutes via PI3K and eNOS activation.
Keyphrases
  • nitric oxide
  • endothelial cells
  • pi k akt
  • signaling pathway