Efficacy and Safety of Sarilumab in patients with COVID19 Pneumonia: A Randomized, Phase III Clinical Trial (SARTRE Study).
Aránzazu Sancho-LópezAntonio F Caballero-BermejoBelén Ruiz-AntoránElena Múñez RubioMercedes García GasallaJuan BuadesMarta González RozasMaría López VelosoAna Muñoz GómezAna Cuenca AbarcaPedro Durán Del CampoFátima IbáñezAlberto Díaz de SantiagoYolanda RomeroJorge CalderónIlduara PintosAdrián Ferre BeltránGustavo Centeno SotoJosé CamposAntonio Ramos MartínezCristina Avendaño-SoláAna Fernández Cruznull nullPublished in: Infectious diseases and therapy (2021)
In hospitalized patients with Covid-19 pneumonia, who were under standard oxygen therapy and who presented analytical inflammatory parameters, an early therapeutic intervention with sarilumab plus standard of care (including corticosteroids) was not shown to be more effective than current standard of care alone. The study was registered at EudraCT with number: 2020-002037-15.