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HER2 assessment by bright-field dual in situ hybridization in cell blocks of recurrent and metastatic breast carcinoma.

Marcia EdelweissAna Paula Martins SebastiaoHandy OenMihaela KracunRene SerretteDara S Ross
Published in: Cancer cytopathology (2019)
All methods of HER2 evaluation were found to accurately identify the amplification status. DISH can be used in tandem with IHC as a reflex assay instead of FISH and is an efficient and reliable method with which to determine HER2 amplification in formalin-fixed CBs.
Keyphrases
  • nucleic acid
  • single cell
  • squamous cell carcinoma
  • small cell lung cancer
  • high throughput
  • cell therapy
  • stem cells
  • mesenchymal stem cells