Zebrafish abcb11b mutant reveals strategies to restore bile excretion impaired by bile salt export pump deficiency.

Jillian L EllisKevin E BoveErin G SchuetzDaniel LeinoC Alexander ValenciaJohn D SchuetzAlexander MiethkeChunyue Yin

Published in: Hepatology (Baltimore, Md.) (2018)

Collectively, these data suggest a model that rapamycin rescues BSEP-deficient phenotypes by prompting alternative transporters to excrete bile salts; multidrug resistance protein 1 is a candidate for such an alternative transporter. (Hepatology 2018;67:1531-1545).

Keyphrases

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amino acid
binding protein
artificial intelligence
replacement therapy
deep learning
smoking cessation