Login / Signup

Zebrafish abcb11b mutant reveals strategies to restore bile excretion impaired by bile salt export pump deficiency.

Jillian L EllisKevin E BoveErin G SchuetzDaniel LeinoC Alexander ValenciaJohn D SchuetzAlexander MiethkeChunyue Yin
Published in: Hepatology (Baltimore, Md.) (2018)
Collectively, these data suggest a model that rapamycin rescues BSEP-deficient phenotypes by prompting alternative transporters to excrete bile salts; multidrug resistance protein 1 is a candidate for such an alternative transporter. (Hepatology 2018;67:1531-1545).
Keyphrases
  • electronic health record
  • mouse model
  • wild type
  • ionic liquid
  • big data
  • amino acid
  • binding protein
  • artificial intelligence
  • replacement therapy
  • deep learning
  • smoking cessation