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Patient-derived, three-dimensional spheroid cultures provide a versatile translational model for the study of organ-confined prostate cancer.

Johannes LinxweilerMarkus HammerStefanie MuhsMoritz KohnAlexej PryalukhinChristian VeithRainer M BohleMichael StöckleKerstin JunkerMatthias Saar
Published in: Journal of cancer research and clinical oncology (2018)
Multicellular 3D spheroids can be generated from patient-derived RP tissue samples and serve as an innovative in vitro model of organ-confined PCa.
Keyphrases
  • prostate cancer
  • radical prostatectomy