Frequency of Comorbid Pathologies and Their Clinical Impact in Multiple System Atrophy.

Hiroaki Sekiya Shunsuke KogaAya MurakamiMichael DeTureOwen A RossRyan J UittiWilliam P CheshireZbigniew K WszolekDennis W Dickson

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

The majority of MSA patients do not have comorbid pathologies, even in advanced age, indicating that MSA is unique among neurodegenerative disorders in this regard. There was minimal clinical impact of comorbid pathologies in MSA. These findings warrant focusing on α-synuclein for the treatment strategy for MSA. © 2023 International Parkinson and Movement Disorder Society.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
patient reported outcomes
combination therapy
replacement therapy