Circulating CD14+ HLA-DRlo/- monocytic cells as a biomarker for epithelial ovarian cancer progression.

Ashley E StenzelScott I AbramsJanine M JosephEllen L GoodeJoseph D TarioPaul K WallaceDivjot KaurAnna-Kay AdamsonMatthew F BuasAmit A LugadeAngela LaslavicSarah E TaylorBrian OrrRobert P EdwardsEsther ElishaevKunle OdunsiJennifer M MongioviJohn Lewis EtterStacey J WinhamScott H KaufmannFrancesmary ModugnoKirsten B Moysich

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

These findings support the potential clinical relevance of CD14+ HLA-DRlo/- monocytic cells in EOC for prognosis and may indicate a non-invasive biomarker to measure disease progression.

Keyphrases

induced apoptosis
cell cycle arrest
cell death
oxidative stress
risk assessment
human health