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Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility.

Aylin Hatice YamacOmer UysalZiya IsmailogluMehmet ErtürkMert CeliktenAhmet BacaksizÜlkan Kılıç
Published in: Cardiology research and practice (2019)
SIRT1 single-nucleotide polymorphisms were associated with premature myocardial infarction, which affected the SIRT1 and endothelial nitric oxide synthase protein expression, irrespective of the underlying SIRT1 genotype.
Keyphrases
  • nitric oxide synthase
  • oxidative stress
  • ischemia reperfusion injury
  • heart failure
  • nitric oxide
  • left ventricular
  • gene expression