Impact of Postoperative Antibiotic Prophylaxis on Surgical Site Infections Rates After Mastectomy with Drains but Without Immediate Reconstruction: A Multicenter, Double-Blinded, Randomized Control Superiority Trial.
Abida K SattarTaleaa MasroorRussell Seth MartinsNida ZahidHania ShahzadRufina SoomroOmema SaleemLubna M VohraSana ZeeshanMuhammad Areeb AshfaqIrum KhanRida NadeemNikhat FatimaAyisha Afzal QureshiFarin F AmersiSyed Faisal MahmoodPublished in: Annals of surgical oncology (2023)
Continuing antibiotic prophylaxis for the duration of indwelling drains after mastectomy without immediate reconstruction offers no additional benefit in terms of SSI reduction. There is a need to update existing guidelines to provide clearer recommendations regarding use of postoperative antibiotic prophylaxis after mastectomy in the setting of indwelling drains.