Is treated HIV infection associated with knee cartilage degeneration and structural changes? A longitudinal study using data from the osteoarthritis initiative.
Yao LiuSarah C ForemanGabby B JosephJan NeumannPhyllis C TienXiaoming LiNancy E LaneMichael C NevittCharles E McCullochThomas M LinkPublished in: BMC musculoskeletal disorders (2019)
Knees of individuals with HIV on ART had a more heterogeneous cartilage matrix, more severe synovitis and abnormalities of the IPFP and SPFP, which may increase the risk of incident knee osteoarthritis.
Keyphrases
- knee osteoarthritis
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv aids
- extracellular matrix
- quality improvement
- cardiovascular disease
- hiv testing
- electronic health record
- hepatitis c virus
- early onset
- anterior cruciate ligament
- big data
- men who have sex with men
- type diabetes
- rheumatoid arthritis
- machine learning
- total knee arthroplasty