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Selective release of miRNAs via extracellular vesicles is associated with house-dust mite allergen-induced airway inflammation.

Yasuhiro GonS MaruokaT InoueK KurodaK YamagishiY KozuS ShikanoK SodaJ LötvallS Hashimoto
Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)
These results indicate that selective sorting of miRNA including Th2 inhibitory miRNAs into AEVs and increase release to the airway after HDM exposure would be involved in the pathogenesis of allergic airway inflammation.
Keyphrases
  • allergic rhinitis
  • high glucose
  • diabetic rats
  • drug induced
  • health risk
  • human health
  • oxidative stress
  • endothelial cells
  • risk assessment
  • polycyclic aromatic hydrocarbons
  • heavy metals
  • atopic dermatitis
  • climate change