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PREVALENCE AND ANTIBIOTIC SUSCEPTIBLITY OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS, COLLECTED AT THAMMASAT UNIVERSITY HOSPITAL, THAILAND, AUGUST 2012 - JULY 2015.

Pimonwan PhokhaphanPholawat TingpejAnucha ApisarnthanarakSumalee Kondo
Published in: The Southeast Asian journal of tropical medicine and public health (2018)
We analyzed data of Staphylococcus aureus isolated from patients attending Thammasat University Hospital, Thailand from August 2012 to July 2015. In total, 232/502 (46%) S. aureus isolates were methicillin-resistant S. aureus (MRSA). There was a declining trend of proportion of MRSA infection, but the prevalence of MRSA in the last year of study remained high (38%). All 32 MRSA-infected outpatients had history of exposure to healthcare facilities during the previous two months and thus were not considered as having community-associated MRSA. In addition, all these strains were negative for pvl, suggesting that these strains were hospital-associated MRSA. All MRSA stains were susceptible to linezolid, teicoplanin and vancomycin, but resistance to erythromycin and clindamycin were nearly 100%. Fifty-two percent and 87% of MRSA strains were susceptible to tetracycline and trimethoprim-sulfamethoxazole, respectively. These results emphasize the necessity of long-term surveillance and monitoring of antimicrobial susceptibility pattern of MRSA.
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