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Effects of SGLT2-Inhibitors on Comprehensive Geriatric Assessment, Biomarkers of Oxidative Stress, and Platelet Activation in Elderly Diabetic Patients with Heart Failure with Preserved Ejection Fraction.

Marcello MagurnoVelia CassanoFrancesco MarucaCarlo Alberto PasturaMarcello DivinoFederica FazioGiandomenico SeveriniElvira ClausiGiuseppe ArmentaroSofia MiceliRaffaele MaioEgidio ImbalzanoFrancesco AndreozziMarta Letizia HribalAngela Sciacqua
Published in: International journal of molecular sciences (2024)
The use of SGLT2i in elderly patients with T2DM and HFpEF significantly contributes to improving CGA scales and biomarkers of OS and PA.
Keyphrases
  • oxidative stress
  • type diabetes
  • dna damage
  • ischemia reperfusion injury
  • wound healing
  • community dwelling
  • induced apoptosis
  • diabetic rats
  • adipose tissue
  • insulin resistance
  • weight loss