Fatal adverse drug reactions: A worldwide perspective in the World Health Organization pharmacovigilance database.
Jean-Louis MontastrucMargaux LafaurieClaire de CanecaudeGeneviève DurrieuAgnès SommetFrançois MontastrucHaleh BagheriPublished in: British journal of clinical pharmacology (2021)
Fatal ADRs registered in a large pharmacovigilance database during the last 10 years correspond to just over 1% of the total number of ADRs. They occurred more in males, after 65 years and with antineoplastic/immunomodulating drugs in general. Our study also highlighted, for the first time, important differences in fatal ADRs between continents and countries.