Intravesical IR-780 instillation prevents radiation cystitis by protecting urothelial integrity.
Jinjin LiChongxing ShenHeping QiuJianwu WangXiaofeng YueLinyong DaiYuandi HuangTong LiQiang FangYi ZhiChunmeng ShiWeibing LiPublished in: Neurourology and urodynamics (2022)
Our data indicate that IR-780 can be used before irradiation to prevent acute urinary mucosal injury and late bladder dysfunction. Moreover, early urothelial impairment plays a significant role in radiation cystitis development.